The MIR155HG was initially identified as a gene that was transcriptionally activated by promoter insertion at a common retroviral integration site in B-cell lymphomas and was formerly called BIC (B-cell Integration Cluster).
Exogenous molecular control in vivo of miR-155 expression may inhibit malignant growth, viral infections, and enhance the progression of cardiovascular diseases. MiR-155 plays a role in various physiological and pathological processes.
MiR-155 is a microRNA that in humans is encoded by the MIR155 host gene or MIR155HG.